Trade brochure
The enclosed brochure provides a more detailed introduction to amino iron and an overview of current studies. amino iron is currently an established low-dose supplement recommended by healthcare professionals and used at several Norwegian blood banks.
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Multicultural brochure
This brochure provides a brief presentation of aminoJern and is intended for users. The brochure has been translated into Urdu, Somali, Arabic, Dari, Polish, Lithuanian and English.
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Studies related to uptake and bioavailability of Ferrochel in amino iron
1. Pineda O, et al ,Effectiveness of iron amino acid chelate on the treatment of iron deficiency anemia in adolescents. Journal of Applied Nutrition 1994,46(1-2): 2-13
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Clinical study in people with iron deficiency anemia. The study compared the effect of 120 mg iron from ferrous sulphate with 30, 60 or 120 mg iron from bisglycinate. It turned out that even 30 mg iron bisglycinate daily corrected Hb within 4 weeks, while ferritin levels only recovered after 6-8 weeks with 30 mg daily. With a daily dose of 60 mg iron bisglycinate, ferritin levels also recovered within 4 weeks.
30 mg daily was thus a sufficient dose to alleviate iron deficiency anemia, while those taking 60 mg recovered more quickly. This study also showed the gentle effect on the stomach and intestines when taking Ferrochel.
2. Milman N, et al. Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial. J. Pernitat Med 2014 42(2); 197-206.
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In this randomized double-blind study, 25 mg iron bisglycinate/Ferrochel was compared with 50 mg ferrous sulphate to prevent iron deficiency in pregnant women. It was shown that 25 mg iron bisglycinate was sufficient to prevent iron deficiency during and after pregnancy.
3. Pineda O et al. Effectiveness of treatment of iron-defi ciency anemia in infants and young children with ferrous bis-glycinate chelate. Nutrition 2001;17(5):381-4.
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This randomized double-blind clinical trial compared the effect of 30, 60 and 120 mg iron from ferrous glycinate with 120 mg ferrous sulfate in 100 children with known iron deficiency anemia and found that even a daily dose as small as 30 mg iron from ferrous bisglycinate/Ferrochel was sufficient to compete with the effect of 120 mg ferrous sulfate in counteracting anemia within 4 weeks.
4. Szarfarc SC et al. Relative effectiveness of iron bisglycinate chelate (Ferrochel) and ferrous sulfate in the control of iron deficiency in pregnant women. Arch Latinoam Nutr.2001 Mar;51(1 Suppl 1):42-47. Nutrition 2001;17(5):381-4.
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In this study, the effect of supplementing with 15 mg iron from ferrous glycinate was compared with 40 mg iron from ferrous sulphate. It was shown that iron bisglycinate/Ferrochel had a significantly better effect on blood parameters during pregnancy than the almost three times higher dose of iron sulphate.
Other relevant studies on Ferrochel in amino iron
- Iost, C et al Repleting hemoglobin in iron deficiency anemia in young children through liquid milk fortification with bioavailable iron amino acid chelate J AmColl Nutr 1998 Apr;17(2):187-94
- M Van Stuijvenberg et al. The efficacy of ferrous bisglycinate and electrolytic iron as fortificants in bread in iron-deficient school children. British Journal of Nutrition 2006 95, 532-538
- Bagna et al. 2018: Efficacy of Supplementation with Iron sulfate Compared to Iron Bisglycinate Chelate in Preterm Infants Ashmead et al. 2001: the absorption and metabolism of iron aminoacid chelate
- Layrisse M et al. Iron Bioavailability in Humans from Break fasts Enriched with Iron Bis-glycine Chelate, Phytates and Polyphenols. J Nutr 2000;130:2195-2199.
- Bovell-Benjamin AC et al. Iron absorption from ferrous bisglycinate and ferrous trisgly cinate in whole maize is regulated by iron status. Am J Clin Nutr.2000;71:1563-69.
Toxicology studies
- Jeppsen RB et al. Safety Evaluation of Ferrous Bisglycinate Chelate. Food and Chemical Toxicology 1999;37:723-31
- Jeppsen RB. Toxicology and safety of Ferrochel and other iron amino acid chelates. Arch Latinoam Nutr. 2001;51(Suppl 1):26-34.
There are many indications that the absorption of iron from Ferrochel is regulated by the body's need for iron, as various studies have shown that the absorption of iron glycine is reduced when hemoglobin increases. This is something that forms the basis for the assessment that the product is safe. In addition, it has been studied in groups such as children and pregnant women without any negative effects.
